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Download Advances in Clinical Chemistry, Vol. 11 by Oscar Bodansky, C. P. Stewart PDF

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By Oscar Bodansky, C. P. Stewart

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Pharmucol. 10, 375-382 (1955). M4. Matassarin, B. , and Delp, M. , The relation of serum iron to hepatocellular disease. Am. J. Med. Sci. 224, 622-626. M5. , The mechanism of iron release from ferritin as related to its biological properties. J. Biol. Chem. 213, 147-160 (1955). M6. , Chodos, R. , Emerson, C. , and Ross, J. , Studies of the anemia and iron metabolism in cancer. J. Clin. Invest. 96, 1248-1262 (1956). M7. Moore, C. , The importance of nutritional factors in the pathogenesis of irondeficiency anemia.

For its success, the iron compound injected must have two properties: it must react readily with siderophilin, and the excess must be removed almost instantaneously from the circulating plasma. These conditions are not fulfilled by colloidal iron-carbohydrate complexes (M3). This is unfortunate because these substances do not cause toxic reactions a t the dosage required. 4. RECOMMENDED PROCEDURE The history of siderophilin and the iron-binding capacity of plasma is shorter than that of the plasma iron, and experience perhaps hardly permits authoritative discussion of the relative merits of the various methods proposed.

N. , and Dean, R. F. ” Edward Arnold, London, 1954. U1. , and Weyer, F. , Eine neue Methode eur gleichzeitigen Mikroktimmung von Eisen und Kupfer in KGrperflhigkeiten. Klin. Wochschr. Bs, 237-238 (1955). V1. , Das Serumeisen, A& Paedial. 28, Suppl. 5, 1-374 (1941). V2. , The cauee of the sex difference in erythrocyte hemoglobin and serum iron levels in human adults. Blwd 6, 874-875. (1950). V3. , “Iron Metabolism and Its Clinical Significance” (E. ). Frederick Muller, London, 1949. V4. , Determination of the unsaturated iron-binding capacity of serum.

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